Male Infertility Being Treated With HCG

Hcg Injections for Male Infertility

In a relatively small number of cases of male infertility, the failure to produce an adequate quality of sperm relates to reduced secretion by the pituitary gland of those hormones necessary to stimulate sperm production. The pituitary gland in the man produces two important hormones-identical to those produced by women-that control testicular function. The first is follicle stimulating hormone (FSH) and the second is luteinizing hormone (LH). Luteinizing hormone’s predominant function is to act on a particular variety of cells in the testicles that produces the male hormone testosterone.

These cells are referred to as Leydig cells. A sustained reduction in FSH production, therefore, is capable of resulting in male infertility. Usually, if there is a reduction in either one of the components, LH or FSH, the other one will also be low. In other words, if a man produces a normal amount of LH and has normal male hormone levels (testosterone, androstenedione, dehydroepiandrosterone), then it is very unlikely that he will have a reduced FSH production. Accordingly, if his sperm function is reduced, it is unlikely to be the result of reduced FSH production by the pituitary gland.

The woman’s cycle usually lasts about 28 days, and under normal circumstances, results in the release of one egg per menstrual cycle. In the man, there exists a continuous production of sperm. In fact, the entire cycle, from initiation to the production of a mature sperm that is capable of fertilizing an egg, takes approximately 100 days. Accordingly, any treatment administered to the man in order to improve sperm production can only be properly assessed after waiting for a period of approximately 100 days. In men, the pituitary gland releases FSH and LH daily in order to meet this need; this is in contrast to the day to day variation that controls the menstrual cycle.

Treat Infertility With HCG Injections

The hormone human chorionic gonadotropin (HCG) is a natural hormone and mimics the effects of LH. In men the HCG is administered in order to stimulate the production of testosterone. Administration of these drugs is usually carried out 3 times per week, for a period of about 100 days before optimal response can be determined. The treatment is, again, relatively harmless and minimal side effects. Like clomiphene, the benefits will be lost when the medications are stopped as would any side effects.

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